The POLIO Study which started in 2005 focuses on examining the shedding and transmission of poliovirus vaccine in children born to HIV infected and uninfected mothers in Chitungwiza, Zimbabwe. This is a longitudinal study following children over 2 years of age to compare the duration of OPV shedding and transmission of the virus within homes over time in an area of high HIV prevalence. The grant is administered through Stanford University funded by the National Institutes of Health (USA).
ZAPP-Regai Dzive Shiri Commercial Sex Work (RDS-CSW)
In 2009 ZAPP-RDS on behalf of UNFPA set up a demonstration sex worker project in Harare and along the Harare Nyamapanda highway. The aims of the project are to: i) reduce HIV acquisition among SWs ii) reduce HIV transmission to their clients iii) improve the reproductive health of SWs iv) improve the rights of SWs. In Harare a drop in centre with clinic facilities was opened at Mbare Polyclinic. Along Harare – Nyamapanda highway mobile clinics were established in Juru, Murewa, Mutoko and Nyamapanda which were visited weekly by a nurse counselor and outreach workers. Twenty peer educators were trained in Harare to support the programme and 25 along the Harare Nyamapanda highway. In 2010 the programme has scaled up to include a drop in centre in Bulawayo modeled on the one in Mbare. The Bulawayo programme will also establish two highway programmes-one on a loop from Bulawayo to Beitbridge and back through Ngundu Halt and the second on the highway linking Bulawayo to Beitbridge.
ZAPP-Regai Dzive Shiri Cotrimoxazole (RDS-CTX)
The objective of the study is to describe the process and barriers to the provision of cotrimoxazole prophylaxis for HIV exposed infants at one urban site in Zimbabwe. The study is divided into three phases as follows:
Phase 1: to describe Zimbabwe national policies and procedures for giving cotrimoxazole to HIV exposed infants and care of HIV infected women before and after delivery.
Phase 2: to describe the cotrimoxazole prophylaxis implementation activities at one urban site. To estimate levels of adherence to cotrimoxazole among HIV exposed infants.
Phase 3: use the data collected in phase 1 and 2 to formulate an evidence-based intervention which aims to improve implementation of cotrimoxazole prophylaxis among HIV exposed infants.
ZAPP-ARROW Young Lives Study
The ZAPP ARROW Young Lives Study is a 2 year project funded by DFID through UZ-CRC ARROW trial. The ARROW young lives study is being conducted at UZ CRC ARROW main trial clinic in Harare. The study is targeting children aged between 11 to 13 years who are already participating in the ARROW trial. These children come from Harare and those who relocated to other areas. The ARROW young lives study seeks to qualitatively describe how the experience of life-long HIV and ART interplays with everyday life for young adolescents in Uganda and Zimbabwe. A particular focus will be on how young people’s experience of informal care and support impact on their experiences of living with HIV and their engagement with HIV treatment. Dr MF Bwakura-Dangarembizi is the Local Principal Investigator and Zivai Mupambireyi is the Project Manager.
A study to systematically monitor voluntary medical male circumcision scale up (SYMMACS)
The aim of this study is to track the adoption of efficiency elements and other voluntary medical male circumcision (VMMC) aspects in four countries: Kenya, South Africa, Tanzania and Zimbabwe. The project is being implemented in all the 10 provinces of Zimbabwe. It is funded by USAID through PSI Zimbabwe. The Principal Investigators are Mr Christopher Samkange and Dr Karin Hatzold.
ZAPP-Family AIDS Initiative
The Elizabeth Glaser Pediatric AIDS Foundation funded Family AIDS Initiative project (with USAID and CIFF funds through Elizabeth Glaser Pediatric Aids Foundation) which started in 2002, supports the national efforts around prevention of mother to child transmission of HIV (MTCT) in Chitungwiza and Gweru City. The project focuses on primary healthcare system support, community mobilization and education to prevent mother to child transmission of HIV/AIDS in Chitungwiza and Gweru City.
ZAPP-Family AIDS Initiative, Save The Children (FAI-SC)
The Save the Children -Zimbabwe funded HIV/AIDS Prevention and Support for Young Children (Urban) which started in 2003, focuses on the welfare of children affected and infected by HIV/AIDS in Chitungwiza.
ZAPP- Regai Dzive Shiri-Behaviour Change (RDS BC)
The Regai Dzive Shiri-Behavioral Change (RDS-BC) project started 2007. The project is core funded by United Nations Family Planning Agency (UNFPA) and National AIDS Council. The RDS-BC Project is implementing the national behaviour change strategy in Masvingo province.
ZAPP-Shaping Adolescents Health in Zimbabwe (SHAZ!)
The ZAPP-SHAZ! Project (SHAZ! Stands for Shaping the Health of Adolescents in Zimbabwe) is started in 2009and is a five year project funded by Pangea Global AIDS Foundation (USA). The project is based in Chitungwiza at Southmed Hospital. The SHAZ! Project works with 16-19 year old girls (Orphans and Vulnerable Children) who are HIV positive in Chitungwiza. The aim is to see: if a girl is economically empowered, will that reduce secondary transmission of HIV, STIs and unwanted pregnancies. The girls will go through life skills training and vocational training.
ZAPP- PATH/PROJECT ARISE (PMTCT PROGRAMME)
CIDA through Population Council is the funder of the PATH/PROJECT ARISE PMTCT Programme from September 2010, supports Ministry of Health and Child Welfare, on prevention of mother to child transmission of HIV (MTCT) in Mashonaland Central Province covering 21 districts. The project focuses on primary healthcare system support, community mobilization and education to prevent mother to child transmission of HIV/AIDS in Mashonaland Central.